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Thus the persistent muscle expression
2018-11-12

Thus, the persistent muscle expression of full length dystrophin remains difficult to achieve currently. Since the discovery of satellite stem PR-619 Supplier and the difficulties met in maintaining their differentiation potential during in vitro culture, several promising alternative candidates fo
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The following are the supplementary related to
2018-11-12

The following are the supplementary related to this article. Acknowledgment We would like to thank for the financial support by the ALF Research Grant, Stockholm County Council; Chinese Scholarship Council, PR China; Craig Hospital Foundation, CO, USA; Magnus Bergvall Foundation, Svenska Läkarsä
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Partial cleavage of CXCL at the
2018-11-09

Partial cleavage of CXCL12 at the N-terminus by distinct peptidases results in loss of chemotactic activity and impairment in CXCR4 receptor affinity (Cho et al., 2010; Delgado et al., 2001; Levesque et al., 2003). The proteolytic cleavage of CXCL12 by matrix metalloproteinase 2 and 9 (MMP-2 and 9)
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Introduction Stem cells including neural stem cells
2018-11-09

Introduction Stem cells, including neural stem cells (NSCs), reside in specialized compartments that contribute to their maintenance. In the embryonic and adult mammalian brains, signals emanating from cells in the niche or the cerebrospinal fluid promote NSC self-renewal and proliferation (Lehtine
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br Results and Discussion br Experimental Procedures
2018-11-09

Results and Discussion Experimental Procedures Author Contributions Acknowledgments We would like to thank Hospital de São João for bone marrow samples and buffy coats. This work had the financial support of FCT/MEC through National Funds and, when applicable, co-financed by the FEDER th
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Introduction The mammalian respiratory tract is normally
2018-11-09

Introduction The mammalian respiratory tract is normally maintained by abundant progenitors that differ in molecular phenotype, differentiation potential, and regulation between airway regions along the proximodistal axis (Hogan et al., 2014; Rackley and Stripp, 2012). Basal cells maintain the pseu
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Introduction The mammalian respiratory tract is normally
2018-11-09

Introduction The mammalian respiratory tract is normally maintained by abundant progenitors that differ in molecular phenotype, differentiation potential, and regulation between airway regions along the proximodistal axis (Hogan et al., 2014; Rackley and Stripp, 2012). Basal cells maintain the pseu
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Fig a shows the tomogram obtained in the conditions when
2018-11-09

Fig. 2a shows the tomogram obtained in the conditions when the studied beeswax sample was placed in the following way: the sides of 17 × 8 cm and 14 × 8 cm were located, respectively, in the xz and yz planes, while the front face of 17 × 15 cm was in the xy plane. According to tomogram measurements,
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Then Eq can be rewritten in the following
2018-11-09

Then Eq. (3) can be rewritten in the following form, replacing the differentiation with respect to the dimensionless time by a variable dotted: Since the parameter T is arbitrary, let us set the following relationship between the newly-emerged multipliers: which separates the common multiplier o
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This evidence is in line with
2018-11-09

This evidence is in line with previous empirical investigations conducted on the UK with BHPS data by Giordano and Lindström (2011) and Lindström and Giordano (2016) which use active participation in associations as structural social capital and an index of self-rated psychological health obtained f
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It is important to consider the self construal of
2018-11-09

It is important to consider the self-construal of salespersons because the self-concept both mediates and regulates behavior. That is, the self-concept “interprets and organizes self-relevant actions and experiences; it dopamine-2 receptor antagonist has motivational consequences, providing the inc
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To evaluate the capacity of the newly
2018-11-09

To evaluate the capacity of the newly isolated recombinants to express BHV-1 UL49.5, total protein was isolated from virus-infected cells and analyzed by immunoblotting. BHV UL49.5 protein only accumulated in BV49.5-infected cells and was not detected in cells infected with the BV49.5-FS variant, wi
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AI-3 Elite suppressors are HIV positive individuals
2018-11-09

Elite suppressors are HIV-positive individuals who have viral loads of AI-3 from four elite suppressors and found that untreated CD8+ T cells were able to suppress infection effectively but that treatment with romidepsin (40nM) or bryostatin-1 (10nM) alone significantly inhibited this suppression b
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The complex interplay between viral escape and Env conformat
2018-11-09

The complex interplay between viral escape and Env conformation observed by Bradley et al. and others gives some pause to reductionist approaches focussing on recapitulating single bNAb specificities by immunisation. Favourable voltage gated sodium channel interactions between different bNAb epitop
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As expected all pups of
2018-11-09

As expected, all pups of PBS-immunized dams showed neurological signs including loss of balance, paresis, and hindlimb paralysis, with 4.62±1.30 of neurological score. However, five out of six pups of MNA-ZIKV-rEfl-immunized dams exhibited neurological illness (no significant difference from the per
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