• In our experiments in mTESR a complex

  2018-10-29

  

  In our experiments in mTESR, a complex medium which is at least more biologically defined than fibroblast conditioned medium supplemented with a serum replacement (i.e. KOSR™) used in our primary screen, SERCA inhibitors and LPA, promoted undifferentiated hESC stemness. Only LPA stimulated a signifi

• Herein to trace the differentiation and analyze human ES or

  2018-10-29

  

  Herein, to trace the differentiation and analyze human ES or iPS cell-derived hepatocytes, we carried out gene targeting of a reporter transgene to the ALB locus and established ALB/monomeric Kusabira orange1 (mKO1) knock-in (ALB/mKo1) hES and hiPS cell lines, and report here the use of these knock-

• NHS-LC-Biotin Main Text One promise of IPSC based cell thera

  2018-10-29

  

  Main Text One promise of IPSC-based cell therapy is that personalized medicine using cells from the patient may be feasible. Somatic cells could be harvested and reprogrammed with integration-free methods to produce a stock of clinically compliant pluripotent cells ready for use at any time in late

• br Results br Discussion Our findings illustrate a transcrip

  2018-10-29

  

  Results Discussion Our findings illustrate a transcriptional circuit involving Cdx4 and Sall4 that is required for the developmental transition from mesoderm to blood formation in zebrafish. By integrating ChIP-seq and expression profiling data from zebrafish embryos, we show that Sall4 shares

• br Experimental Procedures br Acknowledgments

  2018-10-29

  

  Experimental Procedures Acknowledgments We are grateful to S. Yamanaka (University of Kyoto) for providing the plasmid and retroviral vectors through Addgene, and to T. Kitamura (University of Tokyo) for providing PlatE cells. We thank A. Nifuji, H. Ideno, and T. Kamada for helpful discussions

• In RPE transplantation it is widely accepted that grafted

  2018-10-29

  

  In RPE transplantation, it is widely accepted that grafted dna alkylation perform better in terms of their morphology, physiology, and survival when transplanted as sheets rather than in suspension. It appears that environmental factors provided by cell sheets, such as extracellular matrix and adhes

• The following are the supplementary

  2018-10-26

  

  The following are the supplementary data related to this article. Acknowledgments The authors wish to thank Dr. K. Inoue for the S100β/GFP-TG rats, Dr. A.F. Parlow and the NIDDK for the FRAX597 against pituitary hormones, Dr. S. Tanaka at Shizuoka University for the antibody against human ACTH

• FUS also known as Translocated in Liposarcoma TLS is

  2018-10-26

  

  FUS, also known as Translocated in Liposarcoma (TLS), is a DNA/RNA-binding protein containing a glycine-rich region, an RNA recognition motif and a nuclear localization signal (Lattante et al., 2013; Yang et al., 2010). In FALS, more than 50 mutations in the FUS gene have been reported (Lattante et 

• At a global level the analysis of DNA methylation

  2018-10-26

  

  At a global level, the analysis of DNA-methylation profiles provides important insights into molecular and cell growth characteristics of PSC that would otherwise be difficult to identify. Reprogramming-associated variations in X-linked CpG methylation is of particular interest because of the comple

• br Acknowledgment br The study was supported by the Russian

  2018-10-26

  

  Acknowledgment The study was supported by the Russian Foundation for Basic Research (grant no. 14-01-31273mol_a). Introduction The present work discusses the interaction between a charged particle and an ultrashort laser pulse with an intensity I = 107 TW۰cm–2 in vacuum, without the bremsst

• The modal approach assumes that different vibrational modes

  2018-10-26

  

  The modal approach assumes that different vibrational modes of the distributed object are controlled independently. Ref. [2] first proposed to apply this approach to controlling vibrations in elastic systems, and this concept was further developed in Ref. [3]. The problem of arranging the sensors an

• The importance of the ICC has been

  2018-10-26

  

  The importance of the ICC has been widely acknowledged for educational outcomes. ICCs are deemed important because they highlight the differential performance of schools (variation between schools) in terms of student achievement, conditional upon prior student achievement (Goldstein, Huiqi, Rath, &

• br Methods br Results Tables and report summary statistics o

  2018-10-26

  

  Methods Results Tables 2 and 3 report summary statistics of cognitive achievement and growth measures and covariates. Mean height-for-age was at least one standard deviation below that of the reference child at all ages, and there are changes in mean HAZ as children age. Tables 4 and 5 presen

• br Acknowledgement br Introduction The

  2018-10-26

  

  Acknowledgement Introduction The world is currently challenged with global warming, depletion of non-renewable fossil fuel and environmental pollution. The major sources of greenhouse gas emissions are fossil fuels (Endalew et al., 2011). To overcome these challenges, there is a need to find a

• The effect of the Rw composition on the Vs and

  2018-10-26

  

  The effect of the Rw composition on the Vs and Vp in the system Mg2SiO4–Fe2SiO4 at a typical P-T condition of the lower part of the MTZ (21 GPa and 1800 K) is shown in Fig. 5. The calculation was done with the data listed in Table 5. The composition effect is still very prominent: when the Rw change

16650 records 1104/1110 page Previous Next First page 上5页 11011102110311041105 下5页 Last page